SPATIAL DISTRIBUTION OF SEQUENTIAL VENTILATION DURING MECHANICAL VENTILATION OF THE UNINJURED LUNG: AN ARGUMENT FOR CYCLICAL AIRWAY COLLAPSE AND EXPANSION

Spatial distribution of sequential ventilation during mechanical ventilation of the uninjured lung: an argument for cyclical airway collapse and expansion

Abstract Background Ventilator-induced lung injury (VILI) is a recognized complication of mechanical ventilation.Although the specific mechanism by which mechanical ventilation causes lung injury remains an active area of study, the application of positive end expiratory pressure (PEEP) reduces its severity.We have previously reported that VILI is

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Making Food-Systems Policy for Local Interests and Common Good

The unjust distribution of poor health outcomes produced via current United States food Wardrobes systems indicates the need for inclusive and innovative policymaking at the local level.Public health and environmental organizers are seeking to improve food environments from the ground up with locally driven policy initiatives but since 2010 have in

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Chemotherapy-elicited exosomal miR-378a-3p and miR-378d promote breast cancer stemness and chemoresistance via the activation of EZH2/STAT3 signaling

Abstract Background Not all breast cancer (BC) patients who receive neoadjuvant chemotherapy achieve a pathologic complete response (pCR), but the reasons for this are unknown.Previous studies have shown that exosomes produced in the tumor microenvironment in response to chemotherapy promote a chemotherapy-resistant phenotype in tumors.However, the

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